BRD-K64800655_PHA-793887_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K64800655_PHA-793887_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACOT9 acyl-CoA thioesterase 9
ADIRF adipogenesis regulatory factor
ALDOB aldolase B, fructose-bisphosphate
ANXA4 annexin A4
ATF5 activating transcription factor 5
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEP57 centrosomal protein 57kDa
CHN1 chimerin 1
CLU clusterin
FBP1 fructose-1,6-bisphosphatase 1
FBXO11 F-box protein 11
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ORC1 origin recognition complex, subunit 1
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PPAP2B phosphatidic acid phosphatase type 2B
PPL periplakin
PRKACB protein kinase, cAMP-dependent, catalytic, beta
SDC4 syndecan 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC38A1 solute carrier family 38, member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYBA cytochrome b-245, alpha polypeptide
EGR1 early growth response 1
FMO2 flavin containing monooxygenase 2 (non-functional)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
KCTD12 potassium channel tetramerization domain containing 12
KRT14 keratin 14, type I
KRT23 keratin 23, type I
LAPTM5 lysosomal protein transmembrane 5
NCALD neurocalcin delta
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
PADI2 peptidyl arginine deiminase, type II
PCNA proliferating cell nuclear antigen
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK1 polo-like kinase 1
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNF167 ring finger protein 167
SCGB2A2 secretoglobin, family 2A, member 2
SFRP4 secreted frizzled-related protein 4
SNAP25 synaptosomal-associated protein, 25kDa
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
STMN1 stathmin 1
TAC1 tachykinin, precursor 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB6 tubulin, beta 6 class V