BRD-K64800655_PHA-793887_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K64800655_PHA-793887_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CA12 carbonic anhydrase XII
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCND1 cyclin D1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHMP4A charged multivesicular body protein 4A
COL15A1 collagen, type XV, alpha 1
FAR2 fatty acyl CoA reductase 2
GLG1 golgi glycoprotein 1
HSPG2 heparan sulfate proteoglycan 2
IGHM immunoglobulin heavy constant mu
ITM2A integral membrane protein 2A
LAPTM4B lysosomal protein transmembrane 4 beta
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
PDE4DIP phosphodiesterase 4D interacting protein
PDZK1 PDZ domain containing 1
PEG3 paternally expressed 3
PFKM phosphofructokinase, muscle
PROM1 prominin 1
PTPRO protein tyrosine phosphatase, receptor type, O
QDPR quinoid dihydropteridine reductase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
S100A7 S100 calcium binding protein A7
SCG2 secretogranin II
SDC2 syndecan 2
SEPW1 selenoprotein W, 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TMEM47 transmembrane protein 47
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
BAD BCL2-associated agonist of cell death
BMP4 bone morphogenetic protein 4
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EHD1 EH-domain containing 1
GSTP1 glutathione S-transferase pi 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NOTCH2NL notch 2 N-terminal like
NRG1 neuregulin 1
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
PLA2G16 phospholipase A2, group XVI
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD9A RAD9 homolog A (S. pombe)
SFTPB surfactant protein B
SGK1 serum/glucocorticoid regulated kinase 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
ZFP36L1 ZFP36 ring finger protein-like 1