BRD-K64800655_PHA-793887_MDAMB231_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K64800655_PHA-793887_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
CX3CL1 chemokine (C-X3-C motif) ligand 1
DHCR24 24-dehydrocholesterol reductase
FBXL12 F-box and leucine-rich repeat protein 12
GSTM3 glutathione S-transferase mu 3 (brain)
GSTT1 glutathione S-transferase theta 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
IGFBP5 insulin-like growth factor binding protein 5
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NDNF neuron-derived neurotrophic factor
NEU1 sialidase 1 (lysosomal sialidase)
OPN3 opsin 3
PDZK1IP1 PDZK1 interacting protein 1
QPRT quinolinate phosphoribosyltransferase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
VEGFA vascular endothelial growth factor A
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
BRCA1 breast cancer 1, early onset
CHEK2 checkpoint kinase 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
DCK deoxycytidine kinase
EHF ets homologous factor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GMDS GDP-mannose 4,6-dehydratase
HOXC6 homeobox C6
HSPA2 heat shock 70kDa protein 2
IL1R2 interleukin 1 receptor, type II
LTF lactotransferrin
NNMT nicotinamide N-methyltransferase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RRM2 ribonucleotide reductase M2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
UBE2C ubiquitin-conjugating enzyme E2C