BRD-K64800655_PHA-793887_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

132 genes differentially expressed following the BRD-K64800655_PHA-793887_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACOT9 acyl-CoA thioesterase 9
ANKRD10 ankyrin repeat domain 10
ASPH aspartate beta-hydroxylase
BEX1 brain expressed, X-linked 1
CD59 CD59 molecule, complement regulatory protein
CHGB chromogranin B
CYB5R1 cytochrome b5 reductase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DST dystonin
FOLR1 folate receptor 1 (adult)
GAA glucosidase, alpha; acid
GPC3 glypican 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL32 interleukin 32
JAG1 jagged 1
KIAA0125 KIAA0125
KLF4 Kruppel-like factor 4 (gut)
LAMC2 laminin, gamma 2
LPIN1 lipin 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MGLL monoglyceride lipase
MTCL1 microtubule crosslinking factor 1
NEBL nebulette
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PEG10 paternally expressed 10
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
RBP4 retinol binding protein 4, plasma
RFX5 regulatory factor X, 5 (influences HLA class II expression)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SDC4 syndecan 4
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPT6 septin 6
SERTAD2 SERTA domain containing 2
SNAP25 synaptosomal-associated protein, 25kDa
SPATA20 spermatogenesis associated 20
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TSTA3 tissue specific transplantation antigen P35B
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ARMCX2 armadillo repeat containing, X-linked 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF5 activating transcription factor 5
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA2 carbonic anhydrase II
CCNA2 cyclin A2
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDCA3 cell division cycle associated 3
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CENPN centromere protein N
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL1A2 collagen, type I, alpha 2
CP ceruloplasmin (ferroxidase)
DCN decorin
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
ELANE elastase, neutrophil expressed
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBXO5 F-box protein 5
FOXM1 forkhead box M1
GINS2 GINS complex subunit 2 (Psf2 homolog)
GTPBP8 GTP-binding protein 8 (putative)
GTSE1 G-2 and S-phase expressed 1
H2AFV H2A histone family, member V
H2AFX H2A histone family, member X
HAL histidine ammonia-lyase
HIST1H4C histone cluster 1, H4c
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF4A kinesin family member 4A
LMNB1 lamin B1
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
LUM lumican
MCM5 minichromosome maintenance complex component 5
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUSAP1 nucleolar and spindle associated protein 1
PCNA proliferating cell nuclear antigen
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRTN3 proteinase 3
PTTG1 pituitary tumor-transforming 1
RNF130 ring finger protein 130
RRM2 ribonucleotide reductase M2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMC4 structural maintenance of chromosomes 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPC25 SPC25, NDC80 kinetochore complex component
SPP1 secreted phosphoprotein 1
STMN1 stathmin 1
TMEM47 transmembrane protein 47
TMSB15A thymosin beta 15a
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TRMT5 tRNA methyltransferase 5
TTK TTK protein kinase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
USP1 ubiquitin specific peptidase 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)