BRD-K64800655_PHA-793887_HME1_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K64800655_PHA-793887_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BHLHE40 basic helix-loop-helix family, member e40
CD14 CD14 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLU clusterin
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR1 early growth response 1
FABP1 fatty acid binding protein 1, liver
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FXYD3 FXYD domain containing ion transport regulator 3
GTF3A general transcription factor IIIA
HAMP hepcidin antimicrobial peptide
IFI6 interferon, alpha-inducible protein 6
IL1B interleukin 1, beta
LAMB2 laminin, beta 2 (laminin S)
MEF2C myocyte enhancer factor 2C
MYO5C myosin VC
NARFL nuclear prelamin A recognition factor-like
OBSL1 obscurin-like 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PBX1 pre-B-cell leukemia homeobox 1
PPT1 palmitoyl-protein thioesterase 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100P S100 calcium binding protein P
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
UBXN4 UBX domain protein 4
WIF1 WNT inhibitory factor 1
ZMAT3 zinc finger, matrin-type 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
AURKB aurora kinase B
AXIN1 axin 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C10ORF10 chromosome 10 open reading frame 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBR3 carbonyl reductase 3
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCNF cyclin F
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CFLAR CASP8 and FADD-like apoptosis regulator
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
EIF5 eukaryotic translation initiation factor 5
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOOK2 hook microtubule-tethering protein 2
HOXA5 homeobox A5
KDM3A lysine (K)-specific demethylase 3A
KRT14 keratin 14, type I
LAMP5 lysosomal-associated membrane protein family, member 5
NEFL neurofilament, light polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NKX3-1 NK3 homeobox 1
PLAT plasminogen activator, tissue
RBMS1 RNA binding motif, single stranded interacting protein 1
RCOR1 REST corepressor 1
RGS2 regulator of G-protein signaling 2
S100A10 S100 calcium binding protein A10
SHB Src homology 2 domain containing adaptor protein B
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
TBX3 T-box 3
TLE4 transducin-like enhancer of split 4
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TUBB2A tubulin, beta 2A class IIa
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican
WT1 Wilms tumor 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZEB2 zinc finger E-box binding homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2