BRD-K64800655_PHA-793887_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

120 genes differentially expressed following the BRD-K64800655_PHA-793887_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABLIM1 actin binding LIM protein 1
BTBD3 BTB (POZ) domain containing 3
CAPN2 calpain 2, (m/II) large subunit
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
COL4A1 collagen, type IV, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CTSE cathepsin E
DUOX2 dual oxidase 2
EMP1 epithelial membrane protein 1
EPHA2 EPH receptor A2
EXT1 exostosin glycosyltransferase 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FHL2 four and a half LIM domains 2
FKBP14 FK506 binding protein 14, 22 kDa
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLIPR1 GLI pathogenesis-related 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HSPA1A heat shock 70kDa protein 1A
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
IL13RA2 interleukin 13 receptor, alpha 2
ITGA6 integrin, alpha 6
JAG1 jagged 1
KLHL21 kelch-like family member 21
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT6B keratin 6B, type II
LAMC2 laminin, gamma 2
LMO2 LIM domain only 2 (rhombotin-like 1)
MAOB monoamine oxidase B
MECOM MDS1 and EVI1 complex locus
MMP7 matrix metallopeptidase 7
NELL2 NEL-like 2 (chicken)
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PECAM1 platelet/endothelial cell adhesion molecule 1
PI3 peptidase inhibitor 3, skin-derived
PRAME preferentially expressed antigen in melanoma
PROM1 prominin 1
PTRF polymerase I and transcript release factor
PVALB parvalbumin
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC38A1 solute carrier family 38, member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SYNGR1 synaptogyrin 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
VAMP3 vesicle-associated membrane protein 3
VNN1 vanin 1

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AQP3 aquaporin 3 (Gill blood group)
BPHL biphenyl hydrolase-like (serine hydrolase)
C1QB complement component 1, q subcomponent, B chain
C1R complement component 1, r subcomponent
C5 complement component 5
C7 complement component 7
CP ceruloplasmin (ferroxidase)
CPM carboxypeptidase M
CREB3L1 cAMP responsive element binding protein 3-like 1
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FOLR1 folate receptor 1 (adult)
GLTSCR2 glioma tumor suppressor candidate region gene 2
GRB14 growth factor receptor-bound protein 14
GSTZ1 glutathione S-transferase zeta 1
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA8 heat shock 70kDa protein 8
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MME membrane metallo-endopeptidase
NLRP2 NLR family, pyrin domain containing 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RELN reelin
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STC2 stanniocalcin 2
TFF3 trefoil factor 3 (intestinal)
TIAM1 T-cell lymphoma invasion and metastasis 1