BRD-K64754843_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K64754843_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL2 angiopoietin-like 2
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
BPHL biphenyl hydrolase-like (serine hydrolase)
C6ORF62 chromosome 6 open reading frame 62
CCNA1 cyclin A1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CES1 carboxylesterase 1
CHN1 chimerin 1
CLC Charcot-Leyden crystal galectin
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COMP cartilage oligomeric matrix protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPT dermatopontin
DPYSL3 dihydropyrimidinase-like 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GPRC5B G protein-coupled receptor, class C, group 5, member B
GREM1 gremlin 1, DAN family BMP antagonist
IPO13 importin 13
JCHAIN joining chain of multimeric IgA and IgM
LEF1 lymphoid enhancer-binding factor 1
OLFML2A olfactomedin-like 2A
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RPL37A ribosomal protein L37a
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SH3BGRL SH3 domain binding glutamate-rich protein like
SULF1 sulfatase 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CXCL14 chemokine (C-X-C motif) ligand 14
DLC1 DLC1 Rho GTPase activating protein
ETV5 ets variant 5
FAM134B family with sequence similarity 134, member B
FCGBP Fc fragment of IgG binding protein
GRIA2 glutamate receptor, ionotropic, AMPA 2
IGFBP6 insulin-like growth factor binding protein 6
KRT7 keratin 7, type II
MET MET proto-oncogene, receptor tyrosine kinase
MT1E metallothionein 1E
NNMT nicotinamide N-methyltransferase
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
SRGN serglycin
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TLR4 toll-like receptor 4
TRAPPC3 trafficking protein particle complex 3
UBE2S ubiquitin-conjugating enzyme E2S