BRD-K64304398_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K64304398_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABAT 4-aminobutyrate aminotransferase
ALB albumin
ALOX5 arachidonate 5-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
BCL6 B-cell CLL/lymphoma 6
BPHL biphenyl hydrolase-like (serine hydrolase)
C1ORF115 chromosome 1 open reading frame 115
CCND2 cyclin D2
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CPM carboxypeptidase M
CPVL carboxypeptidase, vitellogenic-like
CRLF1 cytokine receptor-like factor 1
CXCL11 chemokine (C-X-C motif) ligand 11
DLK1 delta-like 1 homolog (Drosophila)
DSP desmoplakin
EAPP E2F-associated phosphoprotein
ERBB4 erb-b2 receptor tyrosine kinase 4
FAM129A family with sequence similarity 129, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF13 fibroblast growth factor 13
FOS FBJ murine osteosarcoma viral oncogene homolog
GOLGA8A golgin A8 family, member A
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBD hemoglobin, delta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHEX hematopoietically expressed homeobox
HOXC6 homeobox C6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R1 interleukin 1 receptor, type I
KIF5C kinesin family member 5C
KRT15 keratin 15, type I
LYZ lysozyme
MAPK13 mitogen-activated protein kinase 13
MICB MHC class I polypeptide-related sequence B
NPY1R neuropeptide Y receptor Y1
NTS neurotensin
PCCB propionyl CoA carboxylase, beta polypeptide
PPARD peroxisome proliferator-activated receptor delta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRE protein tyrosine phosphatase, receptor type, E
QPCT glutaminyl-peptide cyclotransferase
RTN1 reticulon 1
SORBS2 sorbin and SH3 domain containing 2
SPTSSA serine palmitoyltransferase, small subunit A
TBL1X transducin (beta)-like 1X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM110 transmembrane protein 110
TMEM30B transmembrane protein 30B
TPD52L1 tumor protein D52-like 1
TXNDC9 thioredoxin domain containing 9
VCAN versican
WNT5A wingless-type MMTV integration site family, member 5A
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ASPN asporin
ATF3 activating transcription factor 3
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CELF2 CUGBP, Elav-like family member 2
COL5A1 collagen, type V, alpha 1
CTSK cathepsin K
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
MECOM MDS1 and EVI1 complex locus
MFAP2 microfibrillar-associated protein 2
MID1 midline 1
NVL nuclear VCP-like
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIH1D1 PIH1 domain containing 1
PTN pleiotrophin
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS16 regulator of G-protein signaling 16
RRAD Ras-related associated with diabetes
SCGB2A1 secretoglobin, family 2A, member 1
VAT1 vesicle amine transport 1