BRD-K64052750_gefitinib_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

64 genes differentially expressed following the BRD-K64052750_gefitinib_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
EGR1 early growth response 1
F13A1 coagulation factor XIII, A1 polypeptide
FOXN3 forkhead box N3
HOXC6 homeobox C6
IGF1R insulin-like growth factor 1 receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
NMU neuromedin U
NNMT nicotinamide N-methyltransferase
PAWR PRKC, apoptosis, WT1, regulator
RGS2 regulator of G-protein signaling 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SESN1 sestrin 1
STAR steroidogenic acute regulatory protein
TMEM47 transmembrane protein 47
TNPO1 transportin 1
TPD52L1 tumor protein D52-like 1
TSC22D3 TSC22 domain family, member 3
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CLDN4 claudin 4
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHA2 EPH receptor A2
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
F3 coagulation factor III (thromboplastin, tissue factor)
FBP1 fructose-1,6-bisphosphatase 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
IL4R interleukin 4 receptor
JCHAIN joining chain of multimeric IgA and IgM
KYNU kynureninase
LYZ lysozyme
MET MET proto-oncogene, receptor tyrosine kinase
MMP9 matrix metallopeptidase 9
NPY neuropeptide Y
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAU plasminogen activator, urokinase
PTN pleiotrophin
SATB1 SATB homeobox 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFTPB surfactant protein B
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SOX11 SRY (sex determining region Y)-box 11
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX1A syntaxin 1A (brain)
VAMP8 vesicle-associated membrane protein 8
XIST X inactive specific transcript (non-protein coding)