BRD-K64052750_gefitinib_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

50 genes differentially expressed following the BRD-K64052750_gefitinib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C4BPA complement component 4 binding protein, alpha
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CXCL12 chemokine (C-X-C motif) ligand 12
IGL immunoglobulin lambda locus
ITM2A integral membrane protein 2A
KIAA0101 KIAA0101
NPY1R neuropeptide Y receptor Y1
PSD3 pleckstrin and Sec7 domain containing 3
S100A8 S100 calcium binding protein A8
SLPI secretory leukocyte peptidase inhibitor
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASCL1 achaete-scute family bHLH transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCND1 cyclin D1
CXCL8 chemokine (C-X-C motif) ligand 8
DFNA5 deafness, autosomal dominant 5
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5A eukaryotic translation initiation factor 5A
FOSL1 FOS-like antigen 1
FZD5 frizzled class receptor 5
FZD7 frizzled class receptor 7
GPX2 glutathione peroxidase 2
HOXA10 homeobox A10
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGA6 integrin, alpha 6
KANK1 KN motif and ankyrin repeat domains 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MAPK13 mitogen-activated protein kinase 13
MTCL1 microtubule crosslinking factor 1
MX2 MX dynamin-like GTPase 2
NFE2L3 nuclear factor, erythroid 2-like 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
RBP1 retinol binding protein 1, cellular
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
SPRED2 sprouty-related, EVH1 domain containing 2
TACSTD2 tumor-associated calcium signal transducer 2
ZFP36 ZFP36 ring finger protein