BRD-K64044582_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K64044582_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCR7 chemokine (C-C motif) receptor 7
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HOXA10 homeobox A10
IGF1 insulin-like growth factor 1 (somatomedin C)
KRT7 keratin 7, type II
MALL mal, T-cell differentiation protein-like
MAOB monoamine oxidase B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NDRG4 NDRG family member 4
NOV nephroblastoma overexpressed
NRCAM neuronal cell adhesion molecule
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SFN stratifin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2
TXNIP thioredoxin interacting protein
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPN asporin
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BEX1 brain expressed, X-linked 1
CCL20 chemokine (C-C motif) ligand 20
CCNE2 cyclin E2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
DHRS2 dehydrogenase/reductase (SDR family) member 2
FBP1 fructose-1,6-bisphosphatase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GAS1 growth arrest-specific 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IFRD2 interferon-related developmental regulator 2
JUN jun proto-oncogene
KLF2 Kruppel-like factor 2
LYZ lysozyme
METTL7A methyltransferase like 7A
PDGFRL platelet-derived growth factor receptor-like
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCI protein kinase C, iota
PSCA prostate stem cell antigen
PSD3 pleckstrin and Sec7 domain containing 3
RGS4 regulator of G-protein signaling 4
SPINK1 serine peptidase inhibitor, Kazal type 1
VCAM1 vascular cell adhesion molecule 1