BRD-K63945320_DIHYDROSAMIDIN_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

125 genes differentially expressed following the BRD-K63945320_DIHYDROSAMIDIN_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACOT13 acyl-CoA thioesterase 13
ADAMDEC1 ADAM-like, decysin 1
ADIRF adipogenesis regulatory factor
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ARG2 arginase 2
BASP1 brain abundant, membrane attached signal protein 1
BID BH3 interacting domain death agonist
BLNK B-cell linker
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CLDN8 claudin 8
CRELD2 cysteine-rich with EGF-like domains 2
CTBP2 C-terminal binding protein 2
CTGF connective tissue growth factor
CTNND1 catenin (cadherin-associated protein), delta 1
CYTIP cytohesin 1 interacting protein
DAXX death-domain associated protein
EHF ets homologous factor
EZR ezrin
FBXL12 F-box and leucine-rich repeat protein 12
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FTH1 ferritin, heavy polypeptide 1
FZD1 frizzled class receptor 1
GATA6 GATA binding protein 6
GJA1 gap junction protein, alpha 1, 43kDa
HAT1 histone acetyltransferase 1
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H4J histone cluster 1, H4j
HIST2H2BE histone cluster 2, H2be
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA4 heat shock 70kDa protein 4
IGHM immunoglobulin heavy constant mu
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MSLN mesothelin
MTSS1 metastasis suppressor 1
NEBL nebulette
NR4A3 nuclear receptor subfamily 4, group A, member 3
NVL nuclear VCP-like
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE8B phosphodiesterase 8B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PPAP2B phosphatidic acid phosphatase type 2B
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSPH phosphoserine phosphatase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRK protein tyrosine phosphatase, receptor type, K
RAB4A RAB4A, member RAS oncogene family
RAI14 retinoic acid induced 14
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNASE6 ribonuclease, RNase A family, k6
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC2 syndecan 2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SOCS2 suppressor of cytokine signaling 2
SRGN serglycin
STON1 stonin 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TESK1 testis-specific kinase 1
THBS1 thrombospondin 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM30B transmembrane protein 30B
TNNT1 troponin T type 1 (skeletal, slow)
TRAP1 TNF receptor-associated protein 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VEGFA vascular endothelial growth factor A
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA7 annexin A7
AREG amphiregulin
BST2 bone marrow stromal cell antigen 2
CFI complement factor I
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FUS FUS RNA binding protein
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HOXC6 homeobox C6
HP haptoglobin
ITM2A integral membrane protein 2A
LEF1 lymphoid enhancer-binding factor 1
MED1 mediator complex subunit 1
NUDCD3 NudC domain containing 3
OAT ornithine aminotransferase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
PLS3 plastin 3
PROM1 prominin 1
QDPR quinoid dihydropteridine reductase
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
SELL selectin L
SRSF5 serine/arginine-rich splicing factor 5
TFF3 trefoil factor 3 (intestinal)
TGFBI transforming growth factor, beta-induced, 68kDa
TNC tenascin C
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TUBB2B tubulin, beta 2B class IIb
VCAN versican
WDR61 WD repeat domain 61