BRD-K63923597_S1147_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K63923597_S1147_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
APOD apolipoprotein D
AREG amphiregulin
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAX BCL2-associated X protein
BIK BCL2-interacting killer (apoptosis-inducing)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CCNG2 cyclin G2
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CERS6 ceramide synthase 6
CES1 carboxylesterase 1
CFB complement factor B
CLU clusterin
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DPT dermatopontin
ERBB2 erb-b2 receptor tyrosine kinase 2
F13A1 coagulation factor XIII, A1 polypeptide
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GSN gelsolin
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
MVP major vault protein
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
S100A14 S100 calcium binding protein A14
SEPP1 selenoprotein P, plasma, 1
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TXNIP thioredoxin interacting protein
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CCNE2 cyclin E2
CDC20 cell division cycle 20
CDC6 cell division cycle 6
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CENPN centromere protein N
CENPU centromere protein U
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
GINS2 GINS complex subunit 2 (Psf2 homolog)
MELK maternal embryonic leucine zipper kinase
NPY neuropeptide Y
PARP2 poly (ADP-ribose) polymerase 2
PLK1 polo-like kinase 1
RFC3 replication factor C (activator 1) 3, 38kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa