BRD-K63828191_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K63828191_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CLIC4 chloride intracellular channel 4
GCH1 GTP cyclohydrolase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
NUPR1 nuclear protein, transcriptional regulator, 1
PALLD palladin, cytoskeletal associated protein
PDGFC platelet derived growth factor C
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RHOBTB3 Rho-related BTB domain containing 3
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CD9 CD9 molecule
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDAH1 dimethylarginine dimethylaminohydrolase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
MMP12 matrix metallopeptidase 12
OLFM1 olfactomedin 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TOX3 TOX high mobility group box family member 3
XIST X inactive specific transcript (non-protein coding)