BRD-K63606607_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

84 genes differentially expressed following the BRD-K63606607_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BIRC2 baculoviral IAP repeat containing 2
BTG3 BTG family, member 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CD200 CD200 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CLIC4 chloride intracellular channel 4
CNN3 calponin 3, acidic
COL11A1 collagen, type XI, alpha 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CYR61 cysteine-rich, angiogenic inducer, 61
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DUSP6 dual specificity phosphatase 6
EFNA1 ephrin-A1
EGR1 early growth response 1
EMP3 epithelial membrane protein 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2R coagulation factor II (thrombin) receptor
FST follistatin
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
H1F0 H1 histone family, member 0
HEBP2 heme binding protein 2
HES1 hes family bHLH transcription factor 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KLK5 kallikrein-related peptidase 5
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
MMP9 matrix metallopeptidase 9
MYH10 myosin, heavy chain 10, non-muscle
PAWR PRKC, apoptosis, WT1, regulator
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNS3 tensin 3
TPD52 tumor protein D52
TSC22D2 TSC22 domain family, member 2
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
ANPEP alanyl (membrane) aminopeptidase
C6ORF62 chromosome 6 open reading frame 62
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CTBP2 C-terminal binding protein 2
DCN decorin
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5 eukaryotic translation initiation factor 5
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
JAK1 Janus kinase 1
MAT2A methionine adenosyltransferase II, alpha
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MME membrane metallo-endopeptidase
MSH6 mutS homolog 6
MYH11 myosin, heavy chain 11, smooth muscle
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRPF4 pre-mRNA processing factor 4
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
REG1A regenerating islet-derived 1 alpha
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TFPI2 tissue factor pathway inhibitor 2
TSPAN8 tetraspanin 8
TXNDC9 thioredoxin domain containing 9
WNT5A wingless-type MMTV integration site family, member 5A
ZDHHC6 zinc finger, DHHC-type containing 6