BRD-K63511615_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K63511615_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CHMP4A charged multivesicular body protein 4A
GUSBP11 glucuronidase, beta pseudogene 11
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
MME membrane metallo-endopeptidase
PLIN2 perilipin 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
STC2 stanniocalcin 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
AHNAK AHNAK nucleoprotein
CAST calpastatin
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPX2 glutathione peroxidase 2
LDLR low density lipoprotein receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKM pyruvate kinase, muscle
PODXL podocalyxin-like
PPARG peroxisome proliferator-activated receptor gamma
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOBTB3 Rho-related BTB domain containing 3
SET SET nuclear proto-oncogene
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSPAN3 tetraspanin 3
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)