BRD-K63504947_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

63 genes differentially expressed following the BRD-K63504947_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
EHD3 EH-domain containing 3
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNGR1 interferon gamma receptor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NAMPT nicotinamide phosphoribosyltransferase
NEFH neurofilament, heavy polypeptide
NEFL neurofilament, light polypeptide
NID2 nidogen 2 (osteonidogen)
NR0B1 nuclear receptor subfamily 0, group B, member 1
PGD phosphogluconate dehydrogenase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIR pirin (iron-binding nuclear protein)
PLBD1 phospholipase B domain containing 1
S100A10 S100 calcium binding protein A10
SGK1 serum/glucocorticoid regulated kinase 1
SNAI2 snail family zinc finger 2
TAC1 tachykinin, precursor 1
TCTA T-cell leukemia translocation altered
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CCND1 cyclin D1
CHN1 chimerin 1
CTSC cathepsin C
DSP desmoplakin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF5A eukaryotic translation initiation factor 5A
EVL Enah/Vasp-like
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IQGAP1 IQ motif containing GTPase activating protein 1
ISOC1 isochorismatase domain containing 1
MT1E metallothionein 1E
MUC1 mucin 1, cell surface associated
PEG10 paternally expressed 10
PRSS23 protease, serine, 23
RAB31 RAB31, member RAS oncogene family
SFRP1 secreted frizzled-related protein 1
SON SON DNA binding protein
TMPRSS3 transmembrane protease, serine 3
TNC tenascin C
TRPS1 trichorhinophalangeal syndrome I
TTC3 tetratricopeptide repeat domain 3