BRD-K63399564_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K63399564_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
BLNK B-cell linker
CD200 CD200 molecule
CPA3 carboxypeptidase A3 (mast cell)
DENND1B DENN/MADD domain containing 1B
DUOX2 dual oxidase 2
IGFBP5 insulin-like growth factor binding protein 5
JCHAIN joining chain of multimeric IgA and IgM
LYZ lysozyme
S100A8 S100 calcium binding protein A8
SELENBP1 selenium binding protein 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMD1 adenosylmethionine decarboxylase 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CXCL13 chemokine (C-X-C motif) ligand 13
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR3 early growth response 3
HEXIM1 hexamethylene bis-acetamide inducible 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NEFH neurofilament, heavy polypeptide
NPY neuropeptide Y
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP62 nucleoporin 62kDa
ODC1 ornithine decarboxylase 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPS4Y1 ribosomal protein S4, Y-linked 1
SFN stratifin
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SSFA2 sperm specific antigen 2
STOM stomatin
SYBU syntabulin (syntaxin-interacting)
TOB1 transducer of ERBB2, 1
TSPAN8 tetraspanin 8