BRD-K63068307_ZSTK-474_LNCAP_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K63068307_ZSTK-474_LNCAP_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANO1 anoctamin 1, calcium activated chloride channel
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CRABP2 cellular retinoic acid binding protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
GAS1 growth arrest-specific 1
IFNGR1 interferon gamma receptor 1
IL1RN interleukin 1 receptor antagonist
KDM3A lysine (K)-specific demethylase 3A
LTBP1 latent transforming growth factor beta binding protein 1
LY6D lymphocyte antigen 6 complex, locus D
MATN2 matrilin 2
MYBPC1 myosin binding protein C, slow type
NRIP3 nuclear receptor interacting protein 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGR2 anterior gradient 2
CAPN1 calpain 1, (mu/I) large subunit
CD200 CD200 molecule
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT4 DNA-damage-inducible transcript 4
FLRT3 fibronectin leucine rich transmembrane protein 3
FOLR1 folate receptor 1 (adult)
GATA3 GATA binding protein 3
GNAS GNAS complex locus
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
LAMB1 laminin, beta 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAN1C1 mannosidase, alpha, class 1C, member 1
MAT2A methionine adenosyltransferase II, alpha
NME4 NME/NM23 nucleoside diphosphate kinase 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
STC1 stanniocalcin 1
STK26 serine/threonine protein kinase 26
VAV3 vav 3 guanine nucleotide exchange factor
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZNF512B zinc finger protein 512B