BRD-K63068307_ZSTK-474_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

143 genes differentially expressed following the BRD-K63068307_ZSTK-474_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPTL2 angiopoietin-like 2
ANKRD36B ankyrin repeat domain 36B
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP9A ATPase, class II, type 9A
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHN2 chimerin 2
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CTSK cathepsin K
CXCL10 chemokine (C-X-C motif) ligand 10
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
ETHE1 ethylmalonic encephalopathy 1
FCGBP Fc fragment of IgG binding protein
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GJA1 gap junction protein, alpha 1, 43kDa
GSDMB gasdermin B
H2AFV H2A histone family, member V
HMGB3 high mobility group box 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LOC100272216 uncharacterized LOC100272216
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MDK midkine (neurite growth-promoting factor 2)
MFAP2 microfibrillar-associated protein 2
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MPDZ multiple PDZ domain protein
N4BP2L1 NEDD4 binding protein 2-like 1
PDGFD platelet derived growth factor D
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTPRE protein tyrosine phosphatase, receptor type, E
PXDN peroxidasin
PXMP2 peroxisomal membrane protein 2, 22kDa
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RGS16 regulator of G-protein signaling 16
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SOX11 SRY (sex determining region Y)-box 11
SOX4 SRY (sex determining region Y)-box 4
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SULF1 sulfatase 1
TCEA2 transcription elongation factor A (SII), 2
TMEM176B transmembrane protein 176B
TMSB15A thymosin beta 15a
TMSB15B thymosin beta 15B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3
VAT1 vesicle amine transport 1
YPEL1 yippee-like 1 (Drosophila)
ZBED8 zinc finger, BED-type containing 8
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADA adenosine deaminase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRG1 adhesion G protein-coupled receptor G1
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
ALDOC aldolase C, fructose-bisphosphate
APOA2 apolipoprotein A-II
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C7 complement component 7
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CD24 CD24 molecule
CLU clusterin
CTSC cathepsin C
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNM1L dynamin 1-like
EGF epidermal growth factor
EIF5A eukaryotic translation initiation factor 5A
ELL2 elongation factor, RNA polymerase II, 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERAP2 endoplasmic reticulum aminopeptidase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM162A family with sequence similarity 162, member A
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GPM6B glycoprotein M6B
HK2 hexokinase 2
IGFBP3 insulin-like growth factor binding protein 3
IL1R2 interleukin 1 receptor, type II
INSIG1 insulin induced gene 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LOC100505650 uncharacterized LOC100505650
MAL mal, T-cell differentiation protein
MINA MYC induced nuclear antigen
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MT1X metallothionein 1X
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKX3-1 NK3 homeobox 1
NPR3 natriuretic peptide receptor 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAX8 paired box 8
PGM1 phosphoglucomutase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPRT quinolinate phosphoribosyltransferase
RCAN1 regulator of calcineurin 1
SCARB1 scavenger receptor class B, member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLPI secretory leukocyte peptidase inhibitor
SMYD3 SET and MYND domain containing 3
SORD sorbitol dehydrogenase
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TNS1 tensin 1
TUBA4A tubulin, alpha 4a
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
VDAC1 voltage-dependent anion channel 1
VLDLR very low density lipoprotein receptor