BRD-K62970326_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K62970326_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
ADORA2B adenosine A2b receptor
ANXA3 annexin A3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CAPG capping protein (actin filament), gelsolin-like
CAPN2 calpain 2, (m/II) large subunit
CD58 CD58 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DUSP14 dual specificity phosphatase 14
EGFR epidermal growth factor receptor
EPHA2 EPH receptor A2
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
JUN jun proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MT1E metallothionein 1E
PALLD palladin, cytoskeletal associated protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
PI3 peptidase inhibitor 3, skin-derived
SDC4 syndecan 4
SFN stratifin
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TJP1 tight junction protein 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
C8ORF4 chromosome 8 open reading frame 4
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HOXA5 homeobox A5
NR2F6 nuclear receptor subfamily 2, group F, member 6
PODXL podocalyxin-like
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5