BRD-K62818989_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K62818989_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHCYL1 adenosylhomocysteinase-like 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CAPG capping protein (actin filament), gelsolin-like
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CNPY3 canopy FGF signaling regulator 3
CRABP2 cellular retinoic acid binding protein 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
ETV5 ets variant 5
FADS2 fatty acid desaturase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IQGAP1 IQ motif containing GTPase activating protein 1
LDLR low density lipoprotein receptor
LGALS1 lectin, galactoside-binding, soluble, 1
MSMO1 methylsterol monooxygenase 1
MTMR11 myotubularin related protein 11
PDLIM1 PDZ and LIM domain 1
PKM pyruvate kinase, muscle
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RNF167 ring finger protein 167
SCGB2A2 secretoglobin, family 2A, member 2
TAGLN2 transgelin 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
CPE carboxypeptidase E
CYCS cytochrome c, somatic
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYNLT3 dynein, light chain, Tctex-type 3
GATA2 GATA binding protein 2
GCH1 GTP cyclohydrolase 1
GREM1 gremlin 1, DAN family BMP antagonist
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXA10 homeobox A10
MAN1A1 mannosidase, alpha, class 1A, member 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PSD3 pleckstrin and Sec7 domain containing 3
RAB40B RAB40B, member RAS oncogene family
S100P S100 calcium binding protein P
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
TBL1X transducin (beta)-like 1X-linked