BRD-K62459624_T5212475_NEU_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

121 genes differentially expressed following the BRD-K62459624_T5212475_NEU_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAG3 BCL2-associated athanogene 3
C6ORF62 chromosome 6 open reading frame 62
CANX calnexin
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CKS2 CDC28 protein kinase regulatory subunit 2
COCH cochlin
CORO1C coronin, actin binding protein, 1C
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFS embryonal Fyn-associated substrate
EGR3 early growth response 3
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5 eukaryotic translation initiation factor 5
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
GPX4 glutathione peroxidase 4
GRN granulin
HMOX1 heme oxygenase 1
HOMER1 homer scaffolding protein 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFI30 interferon, gamma-inducible protein 30
KCTD5 potassium channel tetramerization domain containing 5
KIAA0125 KIAA0125
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGED1 melanoma antigen family D1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MRPL18 mitochondrial ribosomal protein L18
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
NKX3-1 NK3 homeobox 1
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PENK proenkephalin
PFKP phosphofructokinase, platelet
PHGDH phosphoglycerate dehydrogenase
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PSAP prosaposin
RPA3 replication protein A3, 14kDa
RPS2 ribosomal protein S2
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQSTM1 sequestosome 1
TARP TCR gamma alternate reading frame protein
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSPAN13 tetraspanin 13
TXNRD1 thioredoxin reductase 1
VCAN versican
XBP1 X-box binding protein 1
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADGRG6 adhesion G protein-coupled receptor G6
ALDOB aldolase B, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
AQP1 aquaporin 1 (Colton blood group)
AREG amphiregulin
C3 complement component 3
CADM1 cell adhesion molecule 1
CAV1 caveolin 1, caveolae protein, 22kDa
CDC20 cell division cycle 20
CFH complement factor H
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CISD1 CDGSH iron sulfur domain 1
CLIC3 chloride intracellular channel 3
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A2 collagen, type V, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CST6 cystatin E/M
CTGF connective tissue growth factor
EMP1 epithelial membrane protein 1
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
GREM1 gremlin 1, DAN family BMP antagonist
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
LTBP1 latent transforming growth factor beta binding protein 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP85 nucleoporin 85kDa
PCDH7 protocadherin 7
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDGFD platelet derived growth factor D
PLA2G15 phospholipase A2, group XV
POSTN periostin, osteoblast specific factor
SELENBP1 selenium binding protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SNX7 sorting nexin 7
SPON1 spondin 1, extracellular matrix protein
SULF1 sulfatase 1
TCEA2 transcription elongation factor A (SII), 2
TMPRSS3 transmembrane protease, serine 3
TNS1 tensin 1
TNS3 tensin 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TPSB2 tryptase beta 2 (gene/pseudogene)
WWTR1 WW domain containing transcription regulator 1
ZFP36L2 ZFP36 ring finger protein-like 2