BRD-K62300190_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K62300190_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BPHL biphenyl hydrolase-like (serine hydrolase)
CA12 carbonic anhydrase XII
CCDC28A coiled-coil domain containing 28A
CD52 CD52 molecule
CDK19 cyclin-dependent kinase 19
CEMIP cell migration inducing protein, hyaluronan binding
COL3A1 collagen, type III, alpha 1
CTSZ cathepsin Z
DCN decorin
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
FZD5 frizzled class receptor 5
GATA3 GATA binding protein 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HBP1 HMG-box transcription factor 1
HEBP2 heme binding protein 2
HIST1H2BG histone cluster 1, H2bg
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
IFITM1 interferon induced transmembrane protein 1
IGFBP6 insulin-like growth factor binding protein 6
ISOC1 isochorismatase domain containing 1
LAMA4 laminin, alpha 4
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
MZB1 marginal zone B and B1 cell-specific protein
PPAP2B phosphatidic acid phosphatase type 2B
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TMEM140 transmembrane protein 140
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
C3 complement component 3
C7 complement component 7
CAPN2 calpain 2, (m/II) large subunit
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CDC42 cell division cycle 42
CDC45 cell division cycle 45
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR3 early growth response 3
G0S2 G0/G1 switch 2
GEM GTP binding protein overexpressed in skeletal muscle
HSPB8 heat shock 22kDa protein 8
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MATN2 matrilin 2
MGP matrix Gla protein
MSLN mesothelin
NCAM1 neural cell adhesion molecule 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PODXL podocalyxin-like
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCML1 sex comb on midleg-like 1 (Drosophila)
TFRC transferrin receptor
TSPAN8 tetraspanin 8