BRD-K62300190_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K62300190_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASPN asporin
ASS1 argininosuccinate synthase 1
BHLHE41 basic helix-loop-helix family, member e41
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
GRN granulin
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
IGF1R insulin-like growth factor 1 receptor
KRT19 keratin 19, type I
LOC100272216 uncharacterized LOC100272216
LOC100505650 uncharacterized LOC100505650
MAPT microtubule-associated protein tau
MUC5B mucin 5B, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
PLAU plasminogen activator, urokinase
RB1CC1 RB1-inducible coiled-coil 1
SEPP1 selenoprotein P, plasma, 1
SFRP4 secreted frizzled-related protein 4
SQSTM1 sequestosome 1
THBS2 thrombospondin 2
TNS3 tensin 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CAV2 caveolin 2
CCDC86 coiled-coil domain containing 86
DKK1 dickkopf WNT signaling pathway inhibitor 1
GBP1 guanylate binding protein 1, interferon-inducible
GRWD1 glutamate-rich WD repeat containing 1
HSPB8 heat shock 22kDa protein 8
KRT6B keratin 6B, type II
KRT81 keratin 81, type II
LTF lactotransferrin
MMP7 matrix metallopeptidase 7
TRAPPC3 trafficking protein particle complex 3