BRD-K62221994_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K62221994_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BHLHE40 basic helix-loop-helix family, member e40
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD48 CD48 molecule
CD8A CD8a molecule
CHRDL1 chordin-like 1
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EPAS1 endothelial PAS domain protein 1
FAM129A family with sequence similarity 129, member A
HBE1 hemoglobin, epsilon 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIC2 hypermethylated in cancer 2
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
IFITM1 interferon induced transmembrane protein 1
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
LPAR6 lysophosphatidic acid receptor 6
LPIN1 lipin 1
LTF lactotransferrin
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP1B microtubule-associated protein 1B
NUCB2 nucleobindin 2
PSAP prosaposin
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RTN1 reticulon 1
SDF2L1 stromal cell-derived factor 2-like 1
SFRP1 secreted frizzled-related protein 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOCS2 suppressor of cytokine signaling 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS2 thrombospondin 2
TMEM47 transmembrane protein 47
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
CCNE2 cyclin E2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCGBP Fc fragment of IgG binding protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KCTD12 potassium channel tetramerization domain containing 12
KLK10 kallikrein-related peptidase 10
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
S100A7 S100 calcium binding protein A7
SATB1 SATB homeobox 1
TLR4 toll-like receptor 4