BRD-K62169556_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K62169556_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASS1 argininosuccinate synthase 1
CTH cystathionine gamma-lyase
DDIT3 DNA-damage-inducible transcript 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FADS1 fatty acid desaturase 1
GADD45B growth arrest and DNA-damage-inducible, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HK2 hexokinase 2
MGP matrix Gla protein
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
PHGDH phosphoglycerate dehydrogenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSAT1 phosphoserine aminotransferase 1
SLC38A2 solute carrier family 38, member 2
STC2 stanniocalcin 2
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
ECM1 extracellular matrix protein 1
EFNB2 ephrin-B2
GJA1 gap junction protein, alpha 1, 43kDa
HSPH1 heat shock 105kDa/110kDa protein 1
KCTD12 potassium channel tetramerization domain containing 12
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
STIP1 stress-induced phosphoprotein 1