BRD-K61981833_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K61981833_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BMP6 bone morphogenetic protein 6
C10ORF10 chromosome 10 open reading frame 10
CELF2 CUGBP, Elav-like family member 2
CRYAB crystallin, alpha B
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
FHL1 four and a half LIM domains 1
GSTT1 glutathione S-transferase theta 1
HMGN4 high mobility group nucleosomal binding domain 4
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KRT23 keratin 23, type I
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
RHOQ ras homolog family member Q
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRAGD Ras-related GTP binding D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TOX3 TOX high mobility group box family member 3
TPD52 tumor protein D52
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
VIM vimentin
WARS tryptophanyl-tRNA synthetase
WSB1 WD repeat and SOCS box containing 1
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AGR2 anterior gradient 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOD apolipoprotein D
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CYR61 cysteine-rich, angiogenic inducer, 61
EIF4B eukaryotic translation initiation factor 4B
EMX2 empty spiracles homeobox 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASTKD5 FAST kinase domains 5
GLIPR1 GLI pathogenesis-related 1
IGF1 insulin-like growth factor 1 (somatomedin C)
KYNU kynureninase
LBH limb bud and heart development
PAWR PRKC, apoptosis, WT1, regulator
PDLIM5 PDZ and LIM domain 5
PODXL podocalyxin-like
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RGCC regulator of cell cycle
RHOBTB3 Rho-related BTB domain containing 3
SFRP4 secreted frizzled-related protein 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TUBB6 tubulin, beta 6 class V
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon