BRD-K61776140_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K61776140_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASS1 argininosuccinate synthase 1
BHLHE41 basic helix-loop-helix family, member e41
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
FADS1 fatty acid desaturase 1
FKBP14 FK506 binding protein 14, 22 kDa
GADD45B growth arrest and DNA-damage-inducible, beta
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC10 homeobox C10
HOXC6 homeobox C6
IER3 immediate early response 3
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LY96 lymphocyte antigen 96
LYZ lysozyme
METTL7A methyltransferase like 7A
MSMO1 methylsterol monooxygenase 1
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
OLFML2B olfactomedin-like 2B
PRKCDBP protein kinase C, delta binding protein
RHOB ras homolog family member B
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
CA2 carbonic anhydrase II
FAM46A family with sequence similarity 46, member A
MME membrane metallo-endopeptidase
PBX3 pre-B-cell leukemia homeobox 3
PFKP phosphofructokinase, platelet