BRD-K61776140_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K61776140_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATF3 activating transcription factor 3
ATP9A ATPase, class II, type 9A
C10ORF10 chromosome 10 open reading frame 10
CD93 CD93 molecule
CFB complement factor B
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLU clusterin
CPD carboxypeptidase D
CTSB cathepsin B
CTSL cathepsin L
DHRS3 dehydrogenase/reductase (SDR family) member 3
EMP1 epithelial membrane protein 1
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
KCTD12 potassium channel tetramerization domain containing 12
LEPR leptin receptor
METTL7A methyltransferase like 7A
MID1 midline 1
MMD monocyte to macrophage differentiation-associated
MTSS1 metastasis suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NNMT nicotinamide N-methyltransferase
PPAP2B phosphatidic acid phosphatase type 2B
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SERINC5 serine incorporator 5
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SQSTM1 sequestosome 1
SYT17 synaptotagmin XVII
TMEM176B transmembrane protein 176B
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCNA2 cyclin A2
CCNB2 cyclin B2
CTSG cathepsin G
ELANE elastase, neutrophil expressed
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLRT3 fibronectin leucine rich transmembrane protein 3
HOPX HOP homeobox
ITM2A integral membrane protein 2A
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
S100A12 S100 calcium binding protein A12
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SHCBP1 SHC SH2-domain binding protein 1
SRSF6 serine/arginine-rich splicing factor 6
TMEM47 transmembrane protein 47
UBE2C ubiquitin-conjugating enzyme E2C