BRD-K61718261_NCGC00182361-01_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

66 genes differentially expressed following the BRD-K61718261_NCGC00182361-01_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
CCL20 chemokine (C-C motif) ligand 20
CD52 CD52 molecule
CLU clusterin
CTSL cathepsin L
DDIT4 DNA-damage-inducible transcript 4
DSC2 desmocollin 2
DUSP1 dual specificity phosphatase 1
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HSPB8 heat shock 22kDa protein 8
IGFBP3 insulin-like growth factor binding protein 3
IL1RN interleukin 1 receptor antagonist
JUN jun proto-oncogene
KRT16 keratin 16, type I
KRT6A keratin 6A, type II
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MT1M metallothionein 1M
NQO2 NAD(P)H dehydrogenase, quinone 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
SQSTM1 sequestosome 1
TXNRD1 thioredoxin reductase 1
TYMP thymidine phosphorylase
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGR2 anterior gradient 2
AQP1 aquaporin 1 (Colton blood group)
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CDK1 cyclin-dependent kinase 1
CLEC2B C-type lectin domain family 2, member B
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
HES1 hes family bHLH transcription factor 1
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100505650 uncharacterized LOC100505650
MPO myeloperoxidase
MXRA5 matrix-remodelling associated 5
NRN1 neuritin 1
OLFML2A olfactomedin-like 2A
PLAT plasminogen activator, tissue
SFRP1 secreted frizzled-related protein 1
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPDEF SAM pointed domain containing ETS transcription factor
TFF3 trefoil factor 3 (intestinal)
TRIM2 tripartite motif containing 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28