BRD-K61717269_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

106 genes differentially expressed following the BRD-K61717269_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ATF4 activating transcription factor 4
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA9 carbonic anhydrase IX
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHIC2 cysteine-rich hydrophobic domain 2
CLIC3 chloride intracellular channel 3
COL11A1 collagen, type XI, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
DDIT4 DNA-damage-inducible transcript 4
DPYSL4 dihydropyrimidinase-like 4
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM162A family with sequence similarity 162, member A
FAM69A family with sequence similarity 69, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BG histone cluster 1, H2bg
HK2 hexokinase 2
HSPA13 heat shock protein 70kDa family, member 13
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
INSIG2 insulin induced gene 2
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
KDM3A lysine (K)-specific demethylase 3A
LHX2 LIM homeobox 2
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEBL nebulette
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKL phosphofructokinase, liver
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PHGDH phosphoglycerate dehydrogenase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNMA2 paraneoplastic Ma antigen 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
S100P S100 calcium binding protein P
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIK1 salt-inducible kinase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPAG4 sperm associated antigen 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STC2 stanniocalcin 2
TMEM45A transmembrane protein 45A
TNIP1 TNFAIP3 interacting protein 1
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAPN2 calpain 2, (m/II) large subunit
CCNF cyclin F
CD59 CD59 molecule, complement regulatory protein
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FPGS folylpolyglutamate synthase
FZD7 frizzled class receptor 7
HOXA10 homeobox A10
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KCTD12 potassium channel tetramerization domain containing 12
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MOK MOK protein kinase
NR2F2 nuclear receptor subfamily 2, group F, member 2
OXA1L oxidase (cytochrome c) assembly 1-like
PDHX pyruvate dehydrogenase complex, component X
PLK1 polo-like kinase 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PSRC1 proline/serine-rich coiled-coil 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR3 transforming growth factor, beta receptor III
TMPRSS2 transmembrane protease, serine 2
TPX2 TPX2, microtubule-associated
TSPAN8 tetraspanin 8