BRD-K61175124_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K61175124_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
CD24 CD24 molecule
CEMIP cell migration inducing protein, hyaluronan binding
COL9A3 collagen, type IX, alpha 3
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FBP1 fructose-1,6-bisphosphatase 1
FKBP14 FK506 binding protein 14, 22 kDa
FNDC3B fibronectin type III domain containing 3B
GCH1 GTP cyclohydrolase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LDLR low density lipoprotein receptor
MBNL2 muscleblind-like splicing regulator 2
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEBL nebulette
NFIL3 nuclear factor, interleukin 3 regulated
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDZK1IP1 PDZK1 interacting protein 1
PER1 period circadian clock 1
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
RNF167 ring finger protein 167
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQLE squalene epoxidase
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TFF1 trefoil factor 1
THBS2 thrombospondin 2
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
C1S complement component 1, s subcomponent
CD44 CD44 molecule (Indian blood group)
CLEC2B C-type lectin domain family 2, member B
COCH cochlin
HOPX HOP homeobox
KRT5 keratin 5, type II
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
NELL2 NEL-like 2 (chicken)
NME4 NME/NM23 nucleoside diphosphate kinase 4
PTDSS1 phosphatidylserine synthase 1
SEPP1 selenoprotein P, plasma, 1
XCL1 chemokine (C motif) ligand 1