BRD-K61105081_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

78 genes differentially expressed following the BRD-K61105081_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATF3 activating transcription factor 3
BST2 bone marrow stromal cell antigen 2
BTN3A2 butyrophilin, subfamily 3, member A2
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CHRDL1 chordin-like 1
CLEC3B C-type lectin domain family 3, member B
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FABP7 fatty acid binding protein 7, brain
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GBP2 guanylate binding protein 2, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTT1 glutathione S-transferase theta 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IL1B interleukin 1, beta
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LAGE3 L antigen family, member 3
LIMCH1 LIM and calponin homology domains 1
LMCD1 LIM and cysteine-rich domains 1
LPL lipoprotein lipase
MCAM melanoma cell adhesion molecule
MFSD10 major facilitator superfamily domain containing 10
MGP matrix Gla protein
MTA1 metastasis associated 1
PALLD palladin, cytoskeletal associated protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PRDX4 peroxiredoxin 4
RCAN1 regulator of calcineurin 1
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
S100A4 S100 calcium binding protein A4
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SKAP2 src kinase associated phosphoprotein 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMAD3 SMAD family member 3
SYNM synemin, intermediate filament protein
THBS2 thrombospondin 2
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
CCND2 cyclin D2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CSTA cystatin A (stefin A)
FBN2 fibrillin 2
JAG1 jagged 1
MPZL2 myelin protein zero-like 2
SCD5 stearoyl-CoA desaturase 5
SDC1 syndecan 1
SHB Src homology 2 domain containing adaptor protein B
SOX11 SRY (sex determining region Y)-box 11
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRIM29 tripartite motif containing 29
TSPYL5 TSPY-like 5
WT1 Wilms tumor 1