BRD-K60866521_idelalisib_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K60866521_idelalisib_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
BEX1 brain expressed, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
CCND1 cyclin D1
CES1 carboxylesterase 1
CHGB chromogranin B
COL1A1 collagen, type I, alpha 1
CSTA cystatin A (stefin A)
CTTN cortactin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DUSP2 dual specificity phosphatase 2
FOLR1 folate receptor 1 (adult)
GAA glucosidase, alpha; acid
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GNAS GNAS complex locus
HACD1 3-hydroxyacyl-CoA dehydratase 1
IRS2 insulin receptor substrate 2
KRT81 keratin 81, type II
LEF1 lymphoid enhancer-binding factor 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOC283683 uncharacterized LOC283683
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MUC1 mucin 1, cell surface associated
NNMT nicotinamide N-methyltransferase
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTS neurotensin
PAN2 PAN2 poly(A) specific ribonuclease subunit
RGS2 regulator of G-protein signaling 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIK1 salt-inducible kinase 1
SQRDL sulfide quinone reductase-like (yeast)
SRGN serglycin
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
TERT telomerase reverse transcriptase

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AK4 adenylate kinase 4
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ARMCX2 armadillo repeat containing, X-linked 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CELF2 CUGBP, Elav-like family member 2
CTBP2 C-terminal binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DCLK1 doublecortin-like kinase 1
DNM1L dynamin 1-like
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM129A family with sequence similarity 129, member A
HAT1 histone acetyltransferase 1
IL32 interleukin 32
KRAS Kirsten rat sarcoma viral oncogene homolog
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPLA1 lysophospholipase I
MBP myelin basic protein
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDHX pyruvate dehydrogenase complex, component X
PIP prolactin-induced protein
POLR1D polymerase (RNA) I polypeptide D, 16kDa
QKI QKI, KH domain containing, RNA binding
RFC2 replication factor C (activator 1) 2, 40kDa
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A2 S100 calcium binding protein A2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SFRP1 secreted frizzled-related protein 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SRP72 signal recognition particle 72kDa
ZC3H15 zinc finger CCCH-type containing 15