BRD-K60298136_ITE_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K60298136_ITE_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AHNAK AHNAK nucleoprotein
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
C6ORF62 chromosome 6 open reading frame 62
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD36 CD36 molecule (thrombospondin receptor)
CECR1 cat eye syndrome chromosome region, candidate 1
CFLAR CASP8 and FADD-like apoptosis regulator
CXCL13 chemokine (C-X-C motif) ligand 13
DAPK1 death-associated protein kinase 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
HNMT histamine N-methyltransferase
IQGAP2 IQ motif containing GTPase activating protein 2
KLF4 Kruppel-like factor 4 (gut)
LEFTY1 left-right determination factor 1
MLPH melanophilin
MT1E metallothionein 1E
MUC1 mucin 1, cell surface associated
MYBPC1 myosin binding protein C, slow type
NANOG Nanog homeobox
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRP2 NLR family, pyrin domain containing 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PSPH phosphoserine phosphatase
RAD23B RAD23 homolog B (S. cerevisiae)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBM47 RNA binding motif protein 47
RDX radixin
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG5 secretogranin V
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SH3BP4 SH3-domain binding protein 4
SOX9 SRY (sex determining region Y)-box 9
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WASF3 WAS protein family, member 3
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCNB2 cyclin B2
CD320 CD320 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CFD complement factor D (adipsin)
COL4A2 collagen, type IV, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FZD2 frizzled class receptor 2
GTPBP8 GTP-binding protein 8 (putative)
HES1 hes family bHLH transcription factor 1
HOXA5 homeobox A5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
ISG20 interferon stimulated exonuclease gene 20kDa
KRT13 keratin 13, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
MBOAT7 membrane bound O-acyltransferase domain containing 7
MGP matrix Gla protein
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NFE2L2 nuclear factor, erythroid 2-like 2
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NRIP1 nuclear receptor interacting protein 1
NXN nucleoredoxin
PAM peptidylglycine alpha-amidating monooxygenase
PLAT plasminogen activator, tissue
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRAME preferentially expressed antigen in melanoma
PRPF4 pre-mRNA processing factor 4
PSCA prostate stem cell antigen
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM45A transmembrane protein 45A
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM2 tripartite motif containing 2
UBE2J1 ubiquitin-conjugating enzyme E2, J1