BRD-K60297835_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K60297835_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA6 annexin A6
ARG2 arginase 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BEX1 brain expressed, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CD52 CD52 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
COL1A2 collagen, type I, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DPP4 dipeptidyl-peptidase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM13A family with sequence similarity 13, member A
FOLR1 folate receptor 1 (adult)
FXYD5 FXYD domain containing ion transport regulator 5
GLRX glutaredoxin (thioltransferase)
H1F0 H1 histone family, member 0
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KRT19 keratin 19, type I
LAPTM5 lysosomal protein transmembrane 5
LMO3 LIM domain only 3 (rhombotin-like 2)
LXN latexin
LYPD3 LY6/PLAUR domain containing 3
MAN1A1 mannosidase, alpha, class 1A, member 1
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOXD1 monooxygenase, DBH-like 1
MT1M metallothionein 1M
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEFL neurofilament, light polypeptide
NELL2 NEL-like 2 (chicken)
NLGN4X neuroligin 4, X-linked
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
PCP4 Purkinje cell protein 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PNMA2 paraneoplastic Ma antigen 2
PTN pleiotrophin
PTX3 pentraxin 3, long
RAB13 RAB13, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS2 regulator of G-protein signaling 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TAGLN2 transgelin 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM100 transmembrane protein 100
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM2 tripartite motif containing 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VCAM1 vascular cell adhesion molecule 1
VSIG4 V-set and immunoglobulin domain containing 4
WASF1 WAS protein family, member 1

decreased expression

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
CA2 carbonic anhydrase II
CTSG cathepsin G
CXCL13 chemokine (C-X-C motif) ligand 13
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GRWD1 glutamate-rich WD repeat containing 1
HBEGF heparin-binding EGF-like growth factor
JAG1 jagged 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLK11 kallikrein-related peptidase 11
KRT17 keratin 17, type I
MAP2K3 mitogen-activated protein kinase kinase 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH10 myosin, heavy chain 10, non-muscle
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PDGFA platelet-derived growth factor alpha polypeptide
POU2AF1 POU class 2 associating factor 1
PRKCD protein kinase C, delta
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SFRP1 secreted frizzled-related protein 1
SMAD7 SMAD family member 7
TACC1 transforming, acidic coiled-coil containing protein 1
TBX2 T-box 2
TNS3 tensin 3