BRD-K60219430_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K60219430_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOD apolipoprotein D
ASS1 argininosuccinate synthase 1
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
DUSP6 dual specificity phosphatase 6
FOXO4 forkhead box O4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
PIP prolactin-induced protein
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKA aurora kinase A
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CCNF cyclin F
CENPA centromere protein A
CENPE centromere protein E, 312kDa
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PLK1 polo-like kinase 1
TPX2 TPX2, microtubule-associated
TUBB2A tubulin, beta 2A class IIa
TUBB6 tubulin, beta 6 class V
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S