BRD-K60070073_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K60070073_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ALOX5 arachidonate 5-lipoxygenase
AMOTL2 angiomotin like 2
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CEP57 centrosomal protein 57kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
ELANE elastase, neutrophil expressed
FAM129A family with sequence similarity 129, member A
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
FXYD5 FXYD domain containing ion transport regulator 5
GCLM glutamate-cysteine ligase, modifier subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MMP7 matrix metallopeptidase 7
NEB nebulin
NPTX2 neuronal pentraxin II
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK1 proprotein convertase subtilisin/kexin type 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLIN2 perilipin 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRUNE2 prune homolog 2 (Drosophila)
PTPRE protein tyrosine phosphatase, receptor type, E
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN1 reticulon 1
RTN2 reticulon 2
SARS seryl-tRNA synthetase
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRGN serglycin
STC2 stanniocalcin 2
TES testin LIM domain protein
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB3 tribbles pseudokinase 3
TTN titin
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CD81 CD81 molecule
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLNB filamin B, beta
GLUL glutamate-ammonia ligase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
INSIG1 insulin induced gene 1
LTBP1 latent transforming growth factor beta binding protein 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKSL1 MARCKS-like 1
MCUR1 mitochondrial calcium uniporter regulator 1
MUC1 mucin 1, cell surface associated
PEBP1 phosphatidylethanolamine binding protein 1
PLTP phospholipid transfer protein
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKCD protein kinase C, delta
PRODH proline dehydrogenase (oxidase) 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SATB1 SATB homeobox 1
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
STK39 serine threonine kinase 39
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)