BRD-K60067222_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K60067222_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
C3 complement component 3
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CRYAB crystallin, alpha B
CTSZ cathepsin Z
DDR1 discoidin domain receptor tyrosine kinase 1
ENO2 enolase 2 (gamma, neuronal)
F12 coagulation factor XII (Hageman factor)
GGT1 gamma-glutamyltransferase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KRT81 keratin 81, type II
L1CAM L1 cell adhesion molecule
LOC100505650 uncharacterized LOC100505650
MAMLD1 mastermind-like domain containing 1
MAP2K5 mitogen-activated protein kinase kinase 5
OXTR oxytocin receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRR7 proline rich 7 (synaptic)
RPL37A ribosomal protein L37a
S100A10 S100 calcium binding protein A10
SLC16A4 solute carrier family 16, member 4
SLC38A1 solute carrier family 38, member 1
STC1 stanniocalcin 1
TFPI2 tissue factor pathway inhibitor 2
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF1 transmembrane 4 L six family member 1
TNIP1 TNFAIP3 interacting protein 1
TNS3 tensin 3
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BRD3 bromodomain containing 3
CLEC2B C-type lectin domain family 2, member B
COL5A1 collagen, type V, alpha 1
CSNK1A1 casein kinase 1, alpha 1
DLK1 delta-like 1 homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
EPHA3 EPH receptor A3
FGFR2 fibroblast growth factor receptor 2
FLRT2 fibronectin leucine rich transmembrane protein 2
GALC galactosylceramidase
GAS1 growth arrest-specific 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
HOXA5 homeobox A5
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
KIAA0368 KIAA0368
LPAR1 lysophosphatidic acid receptor 1
LPAR6 lysophosphatidic acid receptor 6
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NELL2 NEL-like 2 (chicken)
PBX3 pre-B-cell leukemia homeobox 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100P S100 calcium binding protein P
SCARB2 scavenger receptor class B, member 2
SOCS2 suppressor of cytokine signaling 2
ZNF91 zinc finger protein 91
ZW10 zw10 kinetochore protein