BRD-K60067222_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K60067222_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ANXA4 annexin A4
ARHGAP29 Rho GTPase activating protein 29
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CD24 CD24 molecule
CLC Charcot-Leyden crystal galectin
CRABP2 cellular retinoic acid binding protein 2
CYB5A cytochrome b5 type A (microsomal)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DRAM1 DNA-damage regulated autophagy modulator 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FTH1 ferritin, heavy polypeptide 1
GDF15 growth differentiation factor 15
GSN gelsolin
HBB hemoglobin, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IER3 immediate early response 3
IL1B interleukin 1, beta
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT18 keratin 18, type I
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MCAM melanoma cell adhesion molecule
MFSD10 major facilitator superfamily domain containing 10
MLF1 myeloid leukemia factor 1
NMU neuromedin U
PLS1 plastin 1
PRAME preferentially expressed antigen in melanoma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A4 S100 calcium binding protein A4
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC35F2 solute carrier family 35, member F2
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
TPD52L1 tumor protein D52-like 1
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
AIM2 absent in melanoma 2
ARID4B AT rich interactive domain 4B (RBP1-like)
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCND2 cyclin D2
CELF2 CUGBP, Elav-like family member 2
CEP350 centrosomal protein 350kDa
CTPS1 CTP synthase 1
DICER1 dicer 1, ribonuclease type III
EGFR epidermal growth factor receptor
MCOLN1 mucolipin 1
MRPS2 mitochondrial ribosomal protein S2
NOTCH2 notch 2
NOTCH2NL notch 2 N-terminal like
OSBPL8 oxysterol binding protein-like 8
ZEB1 zinc finger E-box binding homeobox 1