BRD-K59753853_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K59753853_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
BANK1 B-cell scaffold protein with ankyrin repeats 1
CXCL12 chemokine (C-X-C motif) ligand 12
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
JCHAIN joining chain of multimeric IgA and IgM
MAN1A1 mannosidase, alpha, class 1A, member 1
NOV nephroblastoma overexpressed
PON2 paraoxonase 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BACE2 beta-site APP-cleaving enzyme 2
CD9 CD9 molecule
DPT dermatopontin
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
PLTP phospholipid transfer protein
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SOBP sine oculis binding protein homolog (Drosophila)
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX2 sushi-repeat containing protein, X-linked 2
STK39 serine threonine kinase 39
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3