BRD-K59369769_HY-10161_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K59369769_HY-10161_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1C3 aldo-keto reductase family 1, member C3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AURKA aurora kinase A
CCNG2 cyclin G2
CFD complement factor D (adipsin)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EFNA1 ephrin-A1
ERBB3 erb-b2 receptor tyrosine kinase 3
FOXO4 forkhead box O4
HBP1 HMG-box transcription factor 1
HMGB3 high mobility group box 3
INSIG1 insulin induced gene 1
JUP junction plakoglobin
KLHDC2 kelch domain containing 2
MYO6 myosin VI
NDC80 NDC80 kinetochore complex component
NQO1 NAD(P)H dehydrogenase, quinone 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3BGRL SH3 domain binding glutamate-rich protein like
TBL1X transducin (beta)-like 1X-linked
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TTK TTK protein kinase
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CDC25A cell division cycle 25A
CXCL8 chemokine (C-X-C motif) ligand 8
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DPH2 DPH2 homolog (S. cerevisiae)
DUSP6 dual specificity phosphatase 6
EGR2 early growth response 2
EGR3 early growth response 3
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GRWD1 glutamate-rich WD repeat containing 1
HOMER1 homer scaffolding protein 1
IER3 immediate early response 3
INPP1 inositol polyphosphate-1-phosphatase
LIF leukemia inhibitory factor
MAP2K3 mitogen-activated protein kinase kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOLC1 nucleolar and coiled-body phosphoprotein 1
NXT1 nuclear transport factor 2-like export factor 1
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
PNP purine nucleoside phosphorylase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SPRY2 sprouty homolog 2 (Drosophila)
SRM spermidine synthase