BRD-K59317601_INK-128_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

106 genes differentially expressed following the BRD-K59317601_INK-128_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRG6 adhesion G protein-coupled receptor G6
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANO1 anoctamin 1, calcium activated chloride channel
BAD BCL2-associated agonist of cell death
C2CD5 C2 calcium-dependent domain containing 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL15A1 collagen, type XV, alpha 1
EPCAM epithelial cell adhesion molecule
EVI2A ecotropic viral integration site 2A
GREM1 gremlin 1, DAN family BMP antagonist
INHBA inhibin, beta A
ITGA6 integrin, alpha 6
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
MTA1 metastasis associated 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OLFM1 olfactomedin 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP4 secreted frizzled-related protein 4
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TNS3 tensin 3
TSPAN1 tetraspanin 1
XIST X inactive specific transcript (non-protein coding)
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
AK4 adenylate kinase 4
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
AUTS2 autism susceptibility candidate 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BZW2 basic leucine zipper and W2 domains 2
C1ORF116 chromosome 1 open reading frame 116
CD47 CD47 molecule
CFD complement factor D (adipsin)
CKAP4 cytoskeleton-associated protein 4
COL1A2 collagen, type I, alpha 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5A cytochrome b5 type A (microsomal)
DAXX death-domain associated protein
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELOVL5 ELOVL fatty acid elongase 5
ENO1 enolase 1, (alpha)
EPHA3 EPH receptor A3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM162A family with sequence similarity 162, member A
FKBP14 FK506 binding protein 14, 22 kDa
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB8 heat shock 22kDa protein 8
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JMJD6 jumonji domain containing 6
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDM5D lysine (K)-specific demethylase 5D
LDLR low density lipoprotein receptor
LTF lactotransferrin
MDK midkine (neurite growth-promoting factor 2)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLEC malectin
MSMO1 methylsterol monooxygenase 1
MYDGF myeloid-derived growth factor
NDRG1 N-myc downstream regulated 1
NPY neuropeptide Y
NRN1 neuritin 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCP4 Purkinje cell protein 4
PDLIM4 PDZ and LIM domain 4
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PKM pyruvate kinase, muscle
PKP1 plakophilin 1
PLAGL1 pleiomorphic adenoma gene-like 1
PNP purine nucleoside phosphorylase
PRDX4 peroxiredoxin 4
RBP1 retinol binding protein 1, cellular
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOB ras homolog family member B
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPB surfactant protein B
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLN sarcolipin
SMCO4 single-pass membrane protein with coiled-coil domains 4
SQLE squalene epoxidase
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TMEM45A transmembrane protein 45A
TNC tenascin C
TPM4 tropomyosin 4
VDAC1 voltage-dependent anion channel 1
XBP1 X-box binding protein 1
ZNF274 zinc finger protein 274
ZNF652 zinc finger protein 652