BRD-K59317601_INK-128_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K59317601_INK-128_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CHGB chromogranin B
DKK3 dickkopf WNT signaling pathway inhibitor 3
DST dystonin
DUSP10 dual specificity phosphatase 10
EGFR epidermal growth factor receptor
GALC galactosylceramidase
GRIA2 glutamate receptor, ionotropic, AMPA 2
IRS1 insulin receptor substrate 1
LAMC2 laminin, gamma 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MET MET proto-oncogene, receptor tyrosine kinase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1D2 nuclear receptor subfamily 1, group D, member 2
PAM peptidylglycine alpha-amidating monooxygenase
PLCB4 phospholipase C, beta 4
PPAP2C phosphatidic acid phosphatase type 2C
PPL periplakin
RAB40B RAB40B, member RAS oncogene family
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPP1 tripeptidyl peptidase I

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ASNS asparagine synthetase (glutamine-hydrolyzing)
AURKA aurora kinase A
CDC20 cell division cycle 20
DDIT4 DNA-damage-inducible transcript 4
EMP3 epithelial membrane protein 3
GINS1 GINS complex subunit 1 (Psf1 homolog)
HAT1 histone acetyltransferase 1
HMGB2 high mobility group box 2
IGL immunoglobulin lambda locus
KIF20A kinesin family member 20A
KRT19 keratin 19, type I
LMNB1 lamin B1
MGP matrix Gla protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PSPH phosphoserine phosphatase
RFC5 replication factor C (activator 1) 5, 36.5kDa
S100A9 S100 calcium binding protein A9
STEAP1 six transmembrane epithelial antigen of the prostate 1
TPSAB1 tryptase alpha/beta 1