BRD-K59273480_3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6(3H,7H)-dione HOC-1_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K59273480_3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6(3H,7H)-dione HOC-1_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL4 adhesion G protein-coupled receptor L4
BGN biglycan
CAV1 caveolin 1, caveolae protein, 22kDa
CD14 CD14 molecule
CD93 CD93 molecule
CISD1 CDGSH iron sulfur domain 1
CORO1A coronin, actin binding protein, 1A
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GIMAP6 GTPase, IMAP family member 6
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
KIAA0226L KIAA0226-like
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP9 matrix metallopeptidase 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PLN phospholamban
PON3 paraoxonase 3
RGCC regulator of cell cycle
SPARCL1 SPARC-like 1 (hevin)
SULF1 sulfatase 1
THBS2 thrombospondin 2
TMEM176B transmembrane protein 176B

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
CHPT1 choline phosphotransferase 1
IGFBP6 insulin-like growth factor binding protein 6
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
PLAGL1 pleiomorphic adenoma gene-like 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM9SF3 transmembrane 9 superfamily member 3
TOX3 TOX high mobility group box family member 3