BRD-K59058766_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

78 genes differentially expressed following the BRD-K59058766_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA4 annexin A4
ARL14 ADP-ribosylation factor-like 14
CALML5 calmodulin-like 5
CAV1 caveolin 1, caveolae protein, 22kDa
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COMP cartilage oligomeric matrix protein
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ENO2 enolase 2 (gamma, neuronal)
EZR ezrin
FADS2 fatty acid desaturase 2
FBLN1 fibulin 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GLUL glutamate-ammonia ligase
GSE1 Gse1 coiled-coil protein
HIST1H2BG histone cluster 1, H2bg
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
IFI27 interferon, alpha-inducible protein 27
IL1R2 interleukin 1 receptor, type II
INSIG1 insulin induced gene 1
KLF6 Kruppel-like factor 6
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LRRC15 leucine rich repeat containing 15
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MCOLN1 mucolipin 1
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PERP PERP, TP53 apoptosis effector
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPAP2B phosphatidic acid phosphatase type 2B
PPIC peptidylprolyl isomerase C (cyclophilin C)
QPCT glutaminyl-peptide cyclotransferase
RIOK3 RIO kinase 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100P S100 calcium binding protein P
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULF1 sulfatase 1
TOX3 TOX high mobility group box family member 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8
TUFT1 tuftelin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ARMCX3 armadillo repeat containing, X-linked 3
BST2 bone marrow stromal cell antigen 2
CLINT1 clathrin interactor 1
DCPS decapping enzyme, scavenger
DEFB1 defensin, beta 1
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
LPL lipoprotein lipase
LTF lactotransferrin
LYPD1 LY6/PLAUR domain containing 1
MT1F metallothionein 1F
MT1HL1 metallothionein 1H-like 1
MT2A metallothionein 2A
TACC3 transforming, acidic coiled-coil containing protein 3
TFPI2 tissue factor pathway inhibitor 2