BRD-K58853583_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K58853583_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL19 chemokine (C-C motif) ligand 19
CDC42 cell division cycle 42
COL14A1 collagen, type XIV, alpha 1
DSP desmoplakin
FERMT2 fermitin family member 2
FLNA filamin A, alpha
FN1 fibronectin 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IRX5 iroquois homeobox 5
KLF6 Kruppel-like factor 6
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCKS myristoylated alanine-rich protein kinase C substrate
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
ORM1 orosomucoid 1
PDGFC platelet derived growth factor C
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RBMS1 RNA binding motif, single stranded interacting protein 1
RGS2 regulator of G-protein signaling 2
S100A10 S100 calcium binding protein A10
SCGB2A2 secretoglobin, family 2A, member 2
SLIT2 slit homolog 2 (Drosophila)
SOWAHC sosondowah ankyrin repeat domain family member C
SOX9 SRY (sex determining region Y)-box 9
STK26 serine/threonine protein kinase 26
TFF3 trefoil factor 3 (intestinal)
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein
U2AF1 U2 small nuclear RNA auxiliary factor 1

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
BASP1 brain abundant, membrane attached signal protein 1
BET1 Bet1 golgi vesicular membrane trafficking protein
BRCA1 breast cancer 1, early onset
CD38 CD38 molecule
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HOPX HOP homeobox
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF14 kinesin family member 14
KRT7 keratin 7, type II
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NMU neuromedin U
NRN1 neuritin 1
OXLD1 oxidoreductase-like domain containing 1
PDE10A phosphodiesterase 10A
RGS10 regulator of G-protein signaling 10
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQRDL sulfide quinone reductase-like (yeast)
TMEM5 transmembrane protein 5
TRIP6 thyroid hormone receptor interactor 6
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)