BRD-K58772419_AZD-6482_BT20_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K58772419_AZD-6482_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
BST2 bone marrow stromal cell antigen 2
BTG2 BTG family, member 2
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CTSB cathepsin B
CXCL14 chemokine (C-X-C motif) ligand 14
ERBB3 erb-b2 receptor tyrosine kinase 3
GBP2 guanylate binding protein 2, interferon-inducible
HBP1 HMG-box transcription factor 1
HMOX1 heme oxygenase 1
IGHM immunoglobulin heavy constant mu
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
N4BP2L1 NEDD4 binding protein 2-like 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDZK1IP1 PDZK1 interacting protein 1
PERP PERP, TP53 apoptosis effector
RAB31 RAB31, member RAS oncogene family
RSRP1 arginine/serine-rich protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SUSD6 sushi domain containing 6
TMEM50A transmembrane protein 50A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ANXA1 annexin A1
AQP1 aquaporin 1 (Colton blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASRGL1 asparaginase like 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CKS1B CDC28 protein kinase regulatory subunit 1B
DHCR7 7-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
G0S2 G0/G1 switch 2
KCTD12 potassium channel tetramerization domain containing 12
MCM10 minichromosome maintenance complex component 10
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYRF myelin regulatory factor
NFIB nuclear factor I/B
NME4 NME/NM23 nucleoside diphosphate kinase 4
NT5E 5'-nucleotidase, ecto (CD73)
PON3 paraoxonase 3
PPARG peroxisome proliferator-activated receptor gamma
PTPRO protein tyrosine phosphatase, receptor type, O
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC43A3 solute carrier family 43, member 3
SOX9 SRY (sex determining region Y)-box 9
STIP1 stress-induced phosphoprotein 1