BRD-K58698715_4-Methoxy-2-(4-propoxy-phenyl)-quinazoline BRD-K58698715_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K58698715_4-Methoxy-2-(4-propoxy-phenyl)-quinazoline BRD-K58698715_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AEBP1 AE binding protein 1
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CLC Charcot-Leyden crystal galectin
COL11A1 collagen, type XI, alpha 1
COL6A1 collagen, type VI, alpha 1
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
DLX2 distal-less homeobox 2
EMP1 epithelial membrane protein 1
FRY furry homolog (Drosophila)
GPRC5B G protein-coupled receptor, class C, group 5, member B
IGFBP5 insulin-like growth factor binding protein 5
IPO13 importin 13
MAGEA3 melanoma antigen family A3
MAL mal, T-cell differentiation protein
MKNK1 MAP kinase interacting serine/threonine kinase 1
MSLN mesothelin
NARFL nuclear prelamin A recognition factor-like
S100A8 S100 calcium binding protein A8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SULF1 sulfatase 1
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
AGR2 anterior gradient 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BMI1 BMI1 proto-oncogene, polycomb ring finger
CXCL12 chemokine (C-X-C motif) ligand 12
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALC galactosylceramidase
HMGB3 high mobility group box 3
HN1 hematological and neurological expressed 1
HSPB8 heat shock 22kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
IGLV2-23 immunoglobulin lambda variable 2-23
IRF8 interferon regulatory factor 8
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MTERF3 mitochondrial transcription termination factor 3
NNMT nicotinamide N-methyltransferase
NPY neuropeptide Y
RBM47 RNA binding motif protein 47
RET ret proto-oncogene
SPATS2L spermatogenesis associated, serine-rich 2-like
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
UBE2A ubiquitin-conjugating enzyme E2A
XBP1 X-box binding protein 1